Additional Feeding Reveals Differences in Immune Recognition and Growth of <i>Plasmodium</i> Parasites in the Mosquito Host
Hyeogsun Kwon, Maria L. Simões, Rebekah A. Reynolds, George Dimopoulos, Ryan C. Smith
Abstract
, where oocyst size is independent of an additional blood meal. This suggests that human malaria parasites are able to exploit host resources provided by an additional feeding to accelerate their growth. In summary, our data highlight distinct differences in malaria parasite species in evading immune recognition and adapting to mosquito blood feeding. These observations have important, yet previously unexplored, implications for the impact of multiple blood meals on the transmission of malaria.
Topics & Concepts
Blood mealBiologyParasite hostingMalariaMidgutPlasmodium bergheiAnopheles gambiaePlasmodium (life cycle)Plasmodium falciparumImmune systemAnophelesAnopheles stephensiImmunologyZoologyAedes aegyptiLarvaEcologyWorld Wide WebComputer scienceMalaria Research and ControlMosquito-borne diseases and controlInvertebrate Immune Response Mechanisms