Paternal High-Fat Diet Exposure Induces Adverse Effects on Offspring Health: a Systematic Review of Animal Studies
Mariane dos Santos Gonçalves, G. S. Perez, Luciana de Jesus Dantas Ferreira, L. S. Santos, G. S. Cordeiro, Ricardo David Couto, Jairza Maria Barreto Medeiros
Abstract
HIGHLIGHTS The main consequences for the offspring are correlated to metabolic health. Paternal exposure to a high-fat diet induces insulin resistance on offspring. In female offspring induces increased risks of breast cancer. In male offspring induces renal injury and increased triglycerides.
Topics & Concepts
OffspringInsulin resistanceBiologyPhysiologyEndocrinologyInternal medicineMedicineObesityPregnancyGeneticsBirth, Development, and HealthNutritional Studies and DietCancer Risks and Factors