Doxorubicin-loaded folate-mediated pH-responsive micelle based on Bletilla striata polysaccharide: Release mechanism, cellular uptake mechanism, distribution, pharmacokinetics, and antitumor effects
Guangyuan Zhang, Long Huang, Ji Wu, Yuran Liu, Zilu Zhang, Qingxiang Guan
Topics & Concepts
MicelleChemistryDoxorubicinBioavailabilityEndocytosisIn vivoDrug deliveryPharmacologyBiophysicsBiochemistryBiologyAqueous solutionCellChemotherapyOrganic chemistryBiotechnologyGeneticsBiological and pharmacological studies of plantsGinseng Biological Effects and ApplicationsNanoparticle-Based Drug Delivery