[Bis(trifluoroacetoxy)iodo]benzene Mediated C‐3 Selenylation of Pyrido[1,2‐<i>a</i>]Pyrimidin‐4‐Ones Under Ambient Conditions

Abstract

Abstract Herein, we report the [Bis(trifluoroacetoxy)iodo]benzene mediated C−H bond arylselenylation of 4 H ‐Pyrido‐[1,2‐ a ]‐Pyrimidin‐4‐ones using readily available organodiselenides. This methodology is scalable and permits for the generation of a broad spectrum of functionally and structurally diverse selenoether derivatives in very promising yields (up to 98%). Notably, this protocol proceeds at ambient conditions and in the absence of a metal. The application of this methodology for the facile synthesis of ArSe substituted 5 H ‐thiazolo‐pyrido[3,2‐ a ]pyrimidin‐4‐ones is also demonstrated. magnified image

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