Near infrared spectroscopic assessment of loosely and tightly bound cortical bone water
Ramyasri Ailavajhala, William Querido, Chamith S. Rajapakse, Nancy Pleshko
Abstract
was exclusively associated with tightly bound mineral water. We also found significant positive correlations between the NIR mineral absorption bands and the mineral content as determined by an established mid infrared spectroscopic parameter, phosphate/amide I. Moreover, the NIR water data showed correlation trends with tissue mineral density (TMD) in cortical bone tissues. These observations reveal the ability of NIR spectroscopy to non-destructively identify loosely and tightly bound water in bone, which could have further applications in biomineralization and biomedical studies.
Topics & Concepts
Bound waterCortical boneChemistryInfraredSpectroscopyInfrared spectroscopyBiophysicsAnatomyMoleculeOpticsOrganic chemistryBiologyQuantum mechanicsPhysicsBone health and osteoporosis researchBody Composition Measurement TechniquesMarine and environmental studies