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The WKRY transcription factor MdWRKY75 regulates anthocyanins accumulation in apples (Malus domestica)

Mengyu Su, Weifang Zuo, Yicheng Wang, Wenjun Liu, Zongying Zhang, Nan Wang, Xuesen Chen

2022Functional Plant Biology42 citationsDOI

Abstract

Anthocyanins play important roles in plant secondary metabolism. Although previous studies have identified many transcription factors (TFs) that participate in the synthetic pathway of anthocyanins, the regulation mechanism of the pathway remain poorly understood. In this study, we identified a WRKY Group IIc TF, MdWRKY75, which contained a typical WRKYGQK heptapeptide sequence and a C2 H2 -zinc finger structure. Subcellular localisation assays found that MdWRKY75 was located in the nucleus. Overexpression of MdWRKY75 promoted the accumulation of anthocyanins in apple (Malus domestica L.) 'Orin' calli. MdWRKY75 mainly stimulated the accumulation of anthocyanins by binding to the promoter of MYB transcription factor, MdMYB1 . Our research could provide new insights into how WRKY TFs regulate the accumulation of anthocyanins in apples.

Topics & Concepts

WRKY protein domainMalusMYBBiologyTranscription factorZinc fingerAnthocyaninCell biologyBotanyBiochemistryArabidopsisGeneMutantPlant Gene Expression AnalysisPlant biochemistry and biosynthesisPhytochemicals and Antioxidant Activities