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Arsenic induces autophagy-dependent apoptosis via Akt inactivation and AMPK activation signaling pathways leading to neuronal cell death

Shih-Chang Fu, Jhe-Wei Lin, Jui‐Ming Liu, Shing‐Hwa Liu, Kai‐Min Fang, Chin‐Chuan Su, Ren‐Jun Hsu, Chin-Ching Wu, Chun-Fa Huang, Kuan-I Lee, Ya‐Wen Chen

2021NeuroToxicology38 citationsDOI

Topics & Concepts

AutophagyProtein kinase BCell biologyProgrammed cell deathApoptosisAMPKPI3K/AKT/mTOR pathwayChemistryLY294002BiologyPhosphorylationSignal transductionProtein kinase ABiochemistryAutophagy in Disease and TherapyArsenic contamination and mitigationHeme Oxygenase-1 and Carbon Monoxide
Arsenic induces autophagy-dependent apoptosis via Akt inactivation and AMPK activation signaling pathways leading to neuronal cell death | Litcius