BAY 2927088: The first non-covalent, potent, and selective tyrosine kinase inhibitor targeting EGFR exon 20 insertions and C797S resistance mutations in NSCLC
Franziska Siegel, Stephan Siegel, K. Graham, Gizem Karsli-Uzunbas, Daniel Korr, Jens Schroeder, Ulf Boemer, R.C. Hillig, Jérémie Mortier, M. Niehues, Sven Golfier, Volker Schulze, Susanne Menz, Atanas Kamburov, Mario Hermsen, Andrew Cherniak, Knut Eis, Ashley Eheim, Matthew Meyerson, Heidi Greulich
Topics & Concepts
ExonCancer researchMutantEGFR inhibitorsMutationLung cancerEpidermal growth factor receptorMolecular biologyGeneChemistryBiologyMedicineCancerGeneticsInternal medicineLung Cancer Treatments and MutationsCancer therapeutics and mechanismsTuberculosis Research and Epidemiology