Near-infrared upper phenyl-fused BODIPY as a photosensitizer for photothermal–photodynamic therapy
Tao Yu, Dongxiang Zhang, Jie Wang, Chang‐Liang Sun, Tian-Fang Cui, Zhang‐Run Xu, Xin‐Dong Jiang, Jianjun Du
Abstract
The introduction of a ring-fused segment into a BODIPY scaffold promoted a spectral bathochromic-shift and enhanced the intersystem crossing capability by a twisted structure. In this work, we designed and synthesized an upper ring-fused BODIPY with 4-dimethylaminostyryl groups (BBDP), which had excellent optical performance for photothermal-photodynamic therapy.
Topics & Concepts
PhotosensitizerPhotodynamic therapyPhotothermal therapyBODIPYMaterials sciencePhotochemistryInfraredNear-infrared spectroscopyOpticsNanotechnologyFluorescenceChemistryOrganic chemistryPhysicsLuminescence and Fluorescent MaterialsNanoplatforms for cancer theranosticsPorphyrin and Phthalocyanine Chemistry