Recent Advances in the Synthesis of Selenophenes and Their Derivatives
Paola S. Hellwig, Thiago J. Peglow, Filipe Penteado, Luana Bagnoli, Gelson Perin, Eder J. Lenardão
Abstract
The selenophene derivatives are an important class of selenium-based heterocyclics. These compounds play an important role in prospecting new drugs, as well as in the development of new light-emitting materials. During the last years, several methods have been emerging to access the selenophene scaffold, employing a diversity of cyclization-based synthetic strategies, involving specific reaction partners and particularities. This review presents a comprehensive discussion on the recent advances in the synthesis of selenophene-based compounds, starting from different precursors, highlighting the main differences, the advantages, and limitations among them.