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p-Trifluoromethyl- and p-pentafluorothio-substituted curcuminoids of the 2,6-di[(E)-benzylidene)]cycloalkanone type: Syntheses and activities against Leishmania major and Toxoplasma gondii parasites

Ibrahim S. Al Nasr, Riadh Hanachi, Ridha Ben Said, Seyfeddine Rahali, Bahoueddine Tangour, Siddig İbrahim Abdelwahab, Abdullah Farasani, Manal Mohamed Elhassan Taha, Anil Bidwai, Waleed S. Koko, Tariq A. Khan, Rainer Schobert, Bernhard Biersack

2021Bioorganic Chemistry21 citationsDOI

Topics & Concepts

AntiparasiticChemistryToxoplasma gondiiStereochemistryAntiparasitic agentStructure–activity relationshipDocking (animal)Bicyclic moleculeIn vitroBiochemistryPharmacologyBiologyImmunologyNursingAntibodyPathologyMedicineSynthesis and Characterization of Heterocyclic CompoundsCurcumin's Biomedical ApplicationsNatural product bioactivities and synthesis
p-Trifluoromethyl- and p-pentafluorothio-substituted curcuminoids of the 2,6-di[(E)-benzylidene)]cycloalkanone type: Syntheses and activities against Leishmania major and Toxoplasma gondii parasites | Litcius