Immunopathological Mechanisms Underlying Cardiac Damage in Chagas Disease
Mariana Citlalli de Alba-Alvarado, Elia Torres-Gutiérrez, Olivia Reynoso‐Ducoing, Edgar Zenteno, Margarita Cabrera‐Bravo, Yolanda Guevara-Gómez, Paz Marı́a Salazar-Schettino, Norma Rivera-Fernández, Martha Irene Bucio-Torres
Abstract
In Chagas disease, the mechanisms involved in cardiac damage are an active field of study. The factors underlying the evolution of lesions following infection by Trypanosoma cruzi and, in some cases, the persistence of its antigens and the host response, with the ensuing development of clinically observable cardiac damage, are analyzed in this review.
Topics & Concepts
Chagas diseaseTrypanosoma cruziDiseaseImmunologyPersistence (discontinuity)MedicineBiologyInternal medicineParasite hostingComputer scienceEngineeringGeotechnical engineeringWorld Wide WebTrypanosoma species research and implicationsResearch on Leishmaniasis StudiesCardiomyopathy and Myosin Studies