Nickel-catalyzed reductive cross-coupling of polyfluoroarenes with alkyl electrophiles by site-selective C–F bond activation
Longlong Xi, Liting Du, Zhuangzhi Shi
Topics & Concepts
ElectrophileChemistryAlkylRegioselectivityReductive eliminationCatalysisHalideCoupling reactionNickelMedicinal chemistryCombinatorial chemistryOrganic chemistryCatalytic C–H Functionalization MethodsFluorine in Organic ChemistryCatalytic Cross-Coupling Reactions