Engineered Living Materials Based on Adhesin-Mediated Trapping of Programmable Cells
Shuaiqi Guo, Emilien Dubuc, Yahav Rave, Mick Verhagen, Simone A. E. Twisk, Tim van der Hek, Guido J.M. Oerlemans, Maxime C. M. van den Oetelaar, Laura S. van Hazendonk, Mariska Brüls, Bruno V. Eijkens, Pim L. Joostens, Sander R. Keij, Weizhou Xing, Martijn Nijs, Jitske Stalpers, Manoj K. Sharma, Marieke Gerth, Roy J. E. A. Boonen, Kees Verduin, Maarten Merkx, Ilja K. Voets, Tom F. A. de Greef
Abstract
, including the strain resistant to methicillin (MRSA). Our tunable platform allows stable integration of programmable cells in dextran-based hydrogels without compromising free diffusion of macromolecules and could have potential applications in biotechnology and biomedicine.
Topics & Concepts
Bacterial adhesinSynthetic biologyComputational biologyTrappingBiologyGeneticsEcologyGeneEscherichia coli3D Printing in Biomedical ResearchMicro and Nano RoboticsCellular Mechanics and Interactions