Litcius/Paper detail

<i>E. coli</i> “super-contaminates” narrow ducts fostered by broad run-time distribution

Nuris Figueroa-Morales, Aramis Rivera, Rodrigo Soto, Anke Lindner, Ernesto Altshuler, Éric Clément

2020Science Advances62 citationsDOIOpen Access PDF

Abstract

can travel upstream in microfluidic devices over distances of 15 mm in times as short as 15 min. Using a stochastic model relating the run times to the time that bacteria spend on surfaces, we quantitatively reproduce the evolution of the contamination profiles when considering a broad distribution of run times. The experimental data cannot be reproduced using the usually accepted exponential distribution of run times. Our study demonstrates that the run-and-tumble statistics determine macroscopic bacterial transport properties. This effect, which we name "super-contamination," could explain the fast onset of some life-threatening medical emergencies.

Topics & Concepts

Upstream (networking)Distribution (mathematics)Motion (physics)Exponential distributionExponential functionFeature (linguistics)MechanicsMicrofluidicsPhysicsBacterial colonyGamma distributionProbability distributionStochastic modellingBiologyBiological systemStatistical physicsGeologyExponential decayComputer scienceExponential growthStochastic processOpticsBacterial Genetics and BiotechnologyBacterial biofilms and quorum sensingMolecular Communication and Nanonetworks