Exploiting a Rose Bengal-bearing, oxygen-producing nanoparticle for SDT and associated immune-mediated therapeutic effects in the treatment of pancreatic cancer
Dean Nicholas, Heather Nesbitt, Sian Farrell, Keirin Logan, Eva McMullin, Tierna Gillan, Paul Kelly, Declan O’Rourke, Simon Porter, Keith Thomas, Barry O’Hagan, Nikolitsa Nomikou, Bridgeen Callan, John F. Callan, A. P. McHale
Topics & Concepts
Pancreatic cancerSonodynamic therapySystemic administrationCancer researchImmune systemCytotoxic T cellRose bengalTumor hypoxiaChemistryReactive oxygen speciesMedicineHypoxia (environmental)PharmacologyPathologyCancerImmunologyInternal medicineBiologyOxygenRadiation therapyBiochemistryIn vitroIn vivoOrganic chemistryBiotechnologyNanoplatforms for cancer theranosticsCancer Research and TreatmentsCancer, Hypoxia, and Metabolism