Erg6 Acts as a Downstream Effector of the Transcription Factor Flo8 To Regulate Biofilm Formation in Candida albicans
Xueyang Jin, Xiaoyi Luan, Fei Xie, Wenqiang Chang, Hong‐Xiang Lou
Abstract
Biofilm formation by C. albicans hinders its eradication by immune cells and antifungal drugs. Flo8 is an important morphogenetic transcription factor that regulates the biofilm formation and in vivo virulence of C. albicans .
Topics & Concepts
Candida albicansBiofilmErgosterolCorpus albicansVirulenceMicrobiologyVirulence factorEffectorBiologyTranscription factorTranscription (linguistics)SterolYeastCell biologyChemistryBiochemistryGeneBacteriaGeneticsLinguisticsPhilosophyCholesterolAntifungal resistance and susceptibilityFungal Biology and ApplicationsFungal and yeast genetics research