Application of salicylic acid as an eco‐friendly and efficient catalyst for the synthesis of 2,4,6‐triaryl pyridine, 2‐amino‐3‐cyanopyridine, and polyhydroquinoline derivatives
Majid Roozifar, Nourallah Hazeri, Homayoun Faroughi Niya
Abstract
In this study, three eco‐friendly, efficient, and convenient protocols have been reported for one‐pot synthesis of 2,4,6‐triaryl pyridine, 2‐amino‐3‐cyanopyridine, and polyhydroquinoline derivatives using salicylic acid as a catalyst under solvent‐free condition. The reported protocols offer several significant advantages such as the application of a nontoxic, neutral, and cheap catalyst, environmentally friendly conditions, the easy isolation of products by filtering, short reaction times, simple methodology, and good yields.
Topics & Concepts
ChemistryEnvironmentally friendlyPyridineCatalysisSalicylic acidCombinatorial chemistryOrganic chemistrySolventOne-pot synthesisReaction conditionsBiochemistryBiologyEcologyMulticomponent Synthesis of HeterocyclesSynthesis and biological activitySynthesis of Tetrazole Derivatives