Decreased incidence of acute rejection without increased incidence of cytomegalovirus (CMV) infection in kidney transplant recipients receiving rabbit anti‐thymocyte globulin without CMV prophylaxis – a cohort single‐center study
Mayara Ivani de Paula, Mary G. Bowring, Ashton A. Shaffer, Jacqueline Garonzik‐Wang, Adrieli Bessa, Cláudia Rosso Felipe, Marina Pontello Cristelli, Allan B. Massie, José Medina‐Pestana, Dorry L. Segev, Hélio Tedesco‐Silva
Abstract
, P = 0.4). Among low-risk KTR receiving no CMV pharmacological prophylaxis, 3 mg/kg rATG induction was associated with a significant reduction in the incidence of AR without an increased risk of CMV infection, regardless of recipient pretransplant CMV serostatus.
Topics & Concepts
MedicineAnti-thymocyte globulinInternal medicineIncidence (geometry)SerostatusCytomegalovirusGastroenterologySingle CenterRelative riskProportional hazards modelCohortImmunologyTransplantationConfidence intervalViral loadVirusViral diseaseOpticsPhysicsHerpesviridaeCytomegalovirus and herpesvirus researchRenal Transplantation Outcomes and TreatmentsNeurological Complications and Syndromes