Chelerythrine, a novel small molecule targeting IL-2, inhibits melanoma progression by blocking the interaction between IL-2 and its receptor
Okki Cho, Joong-Woon Lee, Hansol Kim, Youngjin Jeong, Tae‐Hwe Heo
Topics & Concepts
IL-2 receptorFOXP3Immune systemChemistryCytotoxic T cellCancer researchInterleukin 2Molecular biologyMelanomaT cellBiologyPharmacologyIn vitroImmunologyBiochemistryBerberine and alkaloids researchPlant chemical constituents analysisSynthesis and bioactivity of alkaloids