Performance of Saliva Specimens for the Molecular Detection of SARS-CoV-2 in the Community Setting: Does Sample Collection Method Matter?
Marta Fernández‐González, Vanesa Agulló, Alba de la Rica, Ana Infante, Mar Carvajal, José Alberto García, Nieves Gonzalo-Jiménez, Claudio Cuartero, Montserrat Ruiz‐García, Carlos de Gregorio, Manuel Sánchez-Molla, Mar Masiá, Félix Gutiérrez
Abstract
Data on the performance of saliva specimens for diagnosing coronavirus disease 2019 (COVID-19) in ambulatory patients are scarce and inconsistent. We assessed saliva-based specimens for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by reverse transcriptase PCR (RT-PCR) in the community setting and compared three different collection methods.
Topics & Concepts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)SalivaCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakSample (material)BetacoronavirusCoronavirus InfectionsVirologySars virusMedicineBiologyChromatographyPathologyChemistryOutbreakInfectious disease (medical specialty)Internal medicineDiseaseSARS-CoV-2 detection and testingAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical Detection