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Siderophore-Mediated Interactions Determine the Disease Suppressiveness of Microbial Consortia

Shaohua Gu, Tianjie Yang, Zhengying Shao, Tao Wang, Kehao Cao, Alexandre Jousset, Ville‐Petri Friman, Cyrus A. Mallon, Xinlan Mei, Zhong Wei, Yangchun Xu, Qirong Shen, Thomas Pommier

2020mSystems77 citationsDOIOpen Access PDF

Abstract

Soil-borne pathogens cause high losses in crop yields globally. The development of environmentally friendly approaches is urgently needed, but is often constrained by complex interactions between root-associated microbes and pathogens. Here, we demonstrate that the interactions within microbial consortia mediated by iron-scavenging siderophores play an important role in reducing pathogen infection and enhancing plant health. This study provides a promising and novel research direction for dealing with a wide range of microbial infections through iron exploitation, which is important for the colonization and infection of both plant and human hosts by pathogens.

Topics & Concepts

SiderophoreBiologyHuman pathogenColonizationPathogenHuman healthMicroorganismMicrobiologyBiotechnologyBacteriaMedicineEnvironmental healthGeneticsLegume Nitrogen Fixing SymbiosisPlant-Microbe Interactions and ImmunityNematode management and characterization studies
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