Design, synthesis, in vitro and in silico investigation of aldose reductase inhibitory effects of new thiazole-based compounds
Belgin Sever, Mehlika Dilek Altıntop, Yeliz Demir, Gülşen Akalın Çiftçi, Şükrü Beydemir, Ahmet Özdemır
Topics & Concepts
ChemistryAldose reductaseIn silicoThiazoleIn vitroInhibitory postsynaptic potentialBiochemistryStereochemistryCombinatorial chemistryPharmacologyEnzymeNeuroscienceGeneBiologyMedicineAldose Reductase and TaurineEicosanoids and Hypertension PharmacologyEnzyme function and inhibition