Metabolomics research on the hepatoprotective effect of cultured bear bile powder in α-naphthylisothiocyanate-induced cholestatic mice
Jiasheng Wu, Su Fang, Wenkai Li, Yifei Li, Yuanyuan Li, Tianming Wang, Li Yang, Shaoyong Liu, Zhengtao Wang, Yueming Ma
Topics & Concepts
GCLCGCLMGlutathioneChemistryCholestasisLiver injuryMultidrug resistance-associated protein 2Bile acidDownregulation and upregulationPharmacologyMetabolomicsMetabolismEffluxGlutamineMetabolic pathwayBile Salt Export PumpGlutamine synthetaseBiochemistryInternal medicineEnzymeTransporterMedicineATP-binding cassette transporterAmino acidGeneChromatographyDrug Transport and Resistance MechanismsDrug-Induced Hepatotoxicity and ProtectionLiver Disease Diagnosis and Treatment