A novel thermal Cas12b from a hot spring bacterium with high target mismatch tolerance and robust DNA cleavage efficiency
Ye Tian, Rui‐Rui Liu, Wen-Dong Xian, Mengjie Xiong, Min Xiao, Wen‐Jun Li
Topics & Concepts
Cleavage (geology)Hot springDNABacteriaSpring (device)ChemistryBiophysicsBiologyGeneticsBiochemistryPhysicsThermodynamicsFracture (geology)PaleontologyCRISPR and Genetic EngineeringRNA and protein synthesis mechanismsChromosomal and Genetic Variations