Discovery of novel dual RAGE/SERT inhibitors for the potential treatment of the comorbidity of Alzheimer's disease and depression
Chao Zhang, Lan Wang, Yixiang Xu, Yunyuan Huang, Junyang Huang, Jin Zhu, Wei Wang, Wangsheng Li, Annan Sun, Xiaokang Li, Haiyan Zhang, Jian Li
Topics & Concepts
Rage (emotion)Depression (economics)PharmacologyComorbidityChemistryIC50AntidepressantPsychiatryInternal medicineMedicinePsychologyIn vitroNeuroscienceBiochemistryAnxietyEconomicsMacroeconomicsAlzheimer's disease research and treatmentsAdvanced Glycation End Products researchComputational Drug Discovery Methods