Cancer cells resistant to immune checkpoint blockade acquire interferon-associated epigenetic memory to sustain T cell dysfunction
Jingya Qiu, Bihui Xu, Darwin Ye, Diqiu Ren, Shangshang Wang, Joseph L. Benci, Yuanming Xu, Hemant Ishwaran, Jean‐Christophe Beltra, E. John Wherry, Junwei Shi, Andy J. Minn
Topics & Concepts
BlockadeImmune checkpointEpigeneticsCancerImmune DysfunctionCell cycle checkpointInterferonCancer researchImmune systemMedicineImmunologyImmunotherapyBiologyCell cycleGeneticsInternal medicineReceptorGeneEpigenetics and DNA MethylationImmune responses and vaccinationsImmune cells in cancer