Toward the nanoscale chemical and physical probing of milk-derived extracellular vesicles using Raman and tip-enhanced Raman spectroscopy
Luca Buccini, Anacleto Proietti, Giancarlo La Penna, Chiara Mancini, Francesco Mura, Stefano Tacconi, Luciana Dini, Marco Rossi, Daniele Passeri
Abstract
Tip enhanced Raman spectroscopy (TERS) increases the spatial resolution of Raman spectroscopy to the nanoscale. The potentiality of TERS is demonstrated on single milk derived extracellular vesicles, allowing the nanoscale chemical investigation of their lipid membrane.
Topics & Concepts
Raman spectroscopyNanoscopic scaleMaterials scienceExtracellular vesiclesNanotechnologyVesicleSpectroscopyChemical engineeringAnalytical Chemistry (journal)BiophysicsChemistryChromatographyMembraneOpticsBiochemistryPhysicsEngineeringCell biologyQuantum mechanicsBiologySpectroscopy Techniques in Biomedical and Chemical ResearchExtracellular vesicles in diseaseAdvancements in Transdermal Drug Delivery