Therapeutic blockade of granulocyte macrophage colony-stimulating factor in COVID-19-associated hyperinflammation: challenges and opportunities
Puja Mehta, Joanna C. Porter, Jessica Manson, John D. Isaacs, Peter Openshaw, Iain B. McInnes, Charlotte Summers, Rachel C. Chambers
Topics & Concepts
MedicineCytokine stormImmunologyARDSMacrophage activation syndromeCytokine release syndromeGranulocyte macrophage colony-stimulating factorCytokineImmunotherapyLungDiseaseImmune systemInternal medicineCoronavirus disease 2019 (COVID-19)Infectious disease (medical specialty)ArthritisChimeric antigen receptorCOVID-19 Clinical Research StudiesRespiratory Support and MechanismsLong-Term Effects of COVID-19