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LC-MS/MS studies for identification and characterization of new forced degradation products of dabrafenib and establishment of their degradation pathway

Parul Grover, Monika Bhardwaj, Lovekesh Mehta

2021Journal of Pharmaceutical and Biomedical Analysis17 citationsDOI

Topics & Concepts

DabrafenibChemistryDegradation (telecommunications)Formic acidTrametinibForced degradationChromatographyHydrogen peroxideMelanomaBiochemistryMetastatic melanomaPhosphorylationMAPK/ERK pathwayCancer researchComputer scienceAmmonium formateVemurafenibBiologyTelecommunicationsMelanoma and MAPK PathwaysComputational Drug Discovery MethodsSynthesis and biological activity
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