Dysbiotic gut microbiota in pancreatic cancer patients form correlation networks with the oral microbiota and prognostic factors.
Hiroki Matsukawa, Noriho Iida, Kazuya Kitamura, Takeshi Terashima, Jun Seishima, Isamu Makino, Takayuki Kannon, Kazuyoshi Hosomichi, Taro Yamashita, Yoshio Sakai, Masao Honda, Tatsuya Yamashita, Eishiro Mizukoshi, Shuichi Kaneko
Abstract
were detected in the PC tissues and formed a network with the fecal and salivary microbes. The dysbiotic gut microbiota in the PC patients formed a complex network with the oral and cancerous microbiota, and gut microbes abundant in the PC patients were closely linked with poor prognostic factors in the network.
Topics & Concepts
Gut floraSalivaBiologyFecesMicrobiologyCancerDysbiosisColorectal cancerImmunologyGeneticsBiochemistryGut microbiota and healthPancreatic and Hepatic Oncology ResearchClostridium difficile and Clostridium perfringens research