Ni‐Catalyzed Regioselective Hydroarylation of 1‐Aryl‐1,3‐Butadienes with Aryl Halides
Chengdong Wang, Yingjie Guo, Xiaoming Wang, Zheng Wang, Kuiling Ding
Abstract
An efficient nickel-catalyzed regioselective hydroarylation of 1,3-dienes with aryl halides and a silane has been developed, affording a range of allylic arenes in good to excellent yields under mild conditions. This method exhibits broad substrate scope, and excellent functional group tolerance. Late-stage modification of complex architectures was demonstrated.
Topics & Concepts
RegioselectivityArylCatalysisAllylic rearrangementHalideSilaneFunctional groupSubstrate (aquarium)ChemistryCombinatorial chemistryNickelOrganic chemistryPolymerOceanographyGeologyAlkylCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsCyclopropane Reaction Mechanisms