Recommendations for the initial management of multisystem inflammatory syndrome temporally related to COVID-19, in children and adolescents
Guillermo Kohn-Loncarica, Ana Fustiñana, Franco Díaz, Juan Camilo Jaramillo-Bustamante, Sebastián González‐Dambrauskas, Pablo Vásquez‐Hoyos, Jaime Fernández‐Sarmiento, Gustavo González, Alejandro Mansur, Javier Montoya Ponce, Roberto Jabornisky
Abstract
Multisystem inflammatory syndrome temporally related to COVID-19 in children and adolescents is a clinical presentation of SARS-CoV-2 infection. It shares some features with Kawasaki disease, toxic shock, sepsis, macrophage activation syndrome, and myocarditis. Few publications have addressed its initial management, which is similar to that proposed for septic shock. This review analyzes such approach based on the characteristics typical of multisystem inflammatory syndrome related to COVID-19 in accordance with the paradigm of an "institutional practice guideline" and suggests therapeutic approach strategies, including early detection, stabilization, referral, specific treatment, and process analysis.