LncRNA HOTAIR promotes myocardial fibrosis in atrial fibrillation through binding with PTBP1 to increase the stability of Wnt5a
Wei Tan, Kun Wang, Yang Xue, Kun Wang, Ning Wang, Tingbo Jiang
Topics & Concepts
HOTAIRGene silencingWnt signaling pathwayCancer researchGene knockdownFibrosisMedicineWNT5ASignal transductionDownregulation and upregulationCell biologyBiologyInternal medicineCell cultureLong non-coding RNAGeneGeneticsBiochemistryCancer-related molecular mechanisms researchIL-33, ST2, and ILC PathwaysConnective Tissue Growth Factor Research