Total synthesis, isolation, surfactant properties, and biological evaluation of ananatosides and related macrodilactone-containing rhamnolipids
Maude Cloutier, Marie-Joëlle Prévost, Serge Lavoie, Thomas Feroldi, Marianne Piochon, Marie‐Christine Groleau, Jean Legault, Sandra Villaume, Jérôme Crouzet, Stéphan Dorey, Mayri A. Díaz De Rienzo, Éric Déziel, Charles Gauthier
Abstract
conformation. Altogether our results suggest that macrolactonization of glycolipids can dramatically interfere with their surfactant properties and biological activity.
Topics & Concepts
Pulmonary surfactantIsolation (microbiology)ChemistryMicrobiologyBiologyBiochemistryCarbohydrate Chemistry and SynthesisSeaweed-derived Bioactive CompoundsMarine Sponges and Natural Products