TRIM25 promotes temozolomide resistance in glioma by regulating oxidative stress and ferroptotic cell death via the ubiquitination of keap1
Jianwei Wei, Li Wang, Yuyan Zhang, Ting Sun, Cai Zhang, Zhonglan Hu, Lijuan Zhou, Xianzhi Liu, Junhu Wan, Liwei Ma
Topics & Concepts
TemozolomideGliomaCancer researchDownregulation and upregulationGene knockdownBiologyKEAP1Oxidative stressUbiquitinCell cultureTranscription factorGeneticsEndocrinologyGeneinterferon and immune responsesMicroRNA in disease regulationRNA Research and Splicing