Synthesis, structure and characterization of new dithiocarbazate-based mixed ligand oxidovanadium(<scp>iv</scp>) complexes: DNA/HSA interaction, cytotoxic activity and DFT studies
Atanu Banerjee, Monalisa Mohanty, Sudhir Lima, Rajib Samanta, Eugenio Garribba, Takahiro Sasamori, Rupam Dinda
Abstract
The synthesis, structure and characterization of mixed ligand oxidovanadium(<sc>iv</sc>) complexes [V<sup>IV</sup>OL<sup>1–2</sup>(L<sup>N–N</sup>)] (<bold>1–3</bold>) are reported. With a view to evaluating their biological activity, their DNA/HSA interaction and cytotoxicity activity have been explored.
Topics & Concepts
ChemistryDNACytotoxicityLigand (biochemistry)StereochemistryCytotoxic T cellCharacterization (materials science)Combinatorial chemistryIn vitroBiochemistryNanotechnologyReceptorMaterials scienceVanadium and Halogenation ChemistryOrganometallic Compounds Synthesis and CharacterizationMetal complexes synthesis and properties