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Synthesis of new substituted pyridine derivatives as potent anti-liver cancer agents through apoptosis induction: In vitro, in vivo, and in silico integrated approaches

Ahmed T. A. Boraei, Elsayed H. Eltamany, Ibrahim A.I. Ali, Sara M. Gebriel, Mohamed S. Nafie

2021Bioorganic Chemistry65 citationsDOI

Topics & Concepts

ChemistryCancer cellLiver cancerAlkylationCancerApoptosisPyridineCytotoxic T cellIn vivoIC50HydrazideStereochemistryIn vitroCombinatorial chemistryBiochemistryMedicinal chemistryOrganic chemistryBiologyGeneticsBiotechnologyCatalysisCancer Mechanisms and TherapySynthesis and biological activityQuinazolinone synthesis and applications
Synthesis of new substituted pyridine derivatives as potent anti-liver cancer agents through apoptosis induction: In vitro, in vivo, and in silico integrated approaches | Litcius