Litcius/Paper detail

Preclinical risk assessment strategy to mitigate the T-cell dependent immunogenicity of protein biotherapeutics: State of the art, challenges and future perspectives

Andrea Di Ianni, Luca Barbero, Tiziana Fraone, Kyra J. Cowan, Federico Riccardi Sirtori

2023Journal of Pharmaceutical and Biomedical Analysis12 citationsDOI

Topics & Concepts

ImmunogenicityImmune systemAntibodyFusion proteinMonoclonal antibodyComputational biologyImmunologyAntigenMedicinePharmacologyChemistryBiologyRecombinant DNABiochemistryGeneBiosimilars and Bioanalytical MethodsMonoclonal and Polyclonal Antibodies ResearchCAR-T cell therapy research