Successful treatment of bullous pemphigoid with dupilumab: a case and brief review of the literature
Maleck Saleh, Matthew Reedy, Helen Torok, Joshua Weaver
Abstract
Bullous pemphigoid is an autoimmune skin disease that results in formation of pruritic blisters. Most cases are treated with a combination of systemic and topical corticosteroids as well as other immunomodulatory drugs. Dupilumab is a fully human monoclonal antibody that acts as an antagonist against IL4Ra traditionally used in the treatment of atopic dermatitis. We present an 80-year-old man with moderate to severe bullous pemphigoid successfully treated with dupilumab.
Topics & Concepts
DupilumabMedicineBullous pemphigoidDermatologyAtopic dermatitisPemphigoidMonoclonal antibodyMonoclonalImmunologyAntibodyAutoimmune Bullous Skin DiseasesUrticaria and Related ConditionsDermatology and Skin Diseases