Current medicinal chemistry strategies in the discovery of novel HIV-1 ribonuclease H inhibitors
Lina Zhang, Fenju Wei, Jiwei Zhang, Chuanfeng Liu, Nerea López‐Carrobles, Xinyong Liu, Luis Menéndez‐Arias, Peng Zhan
Topics & Concepts
RNase HChemistryReverse transcriptaseDrug discoveryHuman immunodeficiency virus (HIV)HeteroduplexRNARibonucleaseDrug developmentComputational biologyDNABiochemistryVirologyDrugBiologyPharmacologyGeneHIV/AIDS drug development and treatmentHIV Research and TreatmentDNA and Nucleic Acid Chemistry