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Protective effects of Nrf2–ARE activator on dopaminergic neuronal loss in Parkinson disease model mice: Possible involvement of heme oxygenase-1

Yuri Inose, Yasuhiko Izumi, Yuki Takada‐Takatori, Akinori Akaike, Yutaka Kōyama, Shuji Kaneko, Toshiaki Kume

2020Neuroscience Letters30 citationsDOI

Topics & Concepts

DopaminergicHeme oxygenaseSubstantia nigraNeurodegenerationOxidative stressActivator (genetics)Downregulation and upregulationParkinson's diseaseHemeDopamineChemistryNeuroscienceBiologyPharmacologyEndocrinologyInternal medicineMedicineBiochemistryEnzymeDiseaseReceptorGeneGenomics, phytochemicals, and oxidative stressHeme Oxygenase-1 and Carbon MonoxideNeuroinflammation and Neurodegeneration Mechanisms
Protective effects of Nrf2–ARE activator on dopaminergic neuronal loss in Parkinson disease model mice: Possible involvement of heme oxygenase-1 | Litcius