Venom peptides – A comprehensive translational perspective in pain management
V Vidya, Raghu Ram Achar, Himathi M.U, N Akshita, Yogish Somayaji T, Vivek Hamse Kameshwar, K. Byrappa, Dinesha Ramadas
Abstract
Venom peptides have been evolving complex therapeutic interventions that potently and selectively modulate a range of targets such as ion channels, receptors, and signaling pathways of physiological processes making it potential therapeutic. Several venom peptides were deduced in vivo for clinical development targeting pain management, diabetes, cardiovascular diseases, antimicrobial activity. Several contributions have been detailed for a clear perspective for a better understanding of venomous animals, their venom, and their pharmacological effects. Here we unravel and summarize the recent advances in wide venom peptides across varieties of species for their therapeutics prospects.