Preventive effect of Chinese dwarf cherry [<i>Cerasus humilis</i> (Bge.) Sok.] fermentation juice on dextran sulfate sodium-induced ulcerative colitis rats through the regulation of IgA and the intestinal immune barrier
Beibei Ran, Chang‐E Guo, Yushi Zhang, Chao Han, Tianli Cao, Houyu Huang, Zeyu Geng, Weidong Li
Abstract
and other beneficial bacteria. The results showed that DSS group rats had immunity and signalling pathway disorders and that CFJ could regulate immune disorders, mainly by regulating the expression of IgA pathway components. Taken together, our results demonstrated that CFJ could regulate changes in the gut microbiota, improve the expression of immune protein-related genes, further regulate intestinal mucosal immune function and maintain intestinal mucosal barrier homeostasis.
Topics & Concepts
LachnospiraceaeImmune systemBacteroidesRoseburiaMicrobiologyBiologyColitisUlcerative colitisChemistryBacteriaImmunologyMedicineInternal medicine16S ribosomal RNADiseaseFirmicutesGeneticsGut microbiota and healthInflammatory Bowel DiseaseProbiotics and Fermented Foods