A novel superparamagnetic powerful guanidine-functionalized γ-Fe<sub>2</sub>O<sub>3</sub> based sulfonic acid recyclable and efficient heterogeneous catalyst for microwave-assisted rapid synthesis of quinazolin-4(3<i>H</i>)-one derivatives in Green media
Fateme Haji Norouzi, Naser Foroughifar, Alireza Khajeh‐Amiri, Hoda Pasdar
Abstract
three-component condensation reaction between anthranilic acid, acetic anhydride and different amines under microwave irradiation and solvent-free conditions (4a-q). XRD, FT-IR, FE-SEM, TGA, VSM and EDX were used to characterize this new magnetic organocatalyst. Outstanding performance, short response time (15-30 min), simple operation, easy work-up procedure, and avoidance of toxic catalysts can be regarded as its significant advantages. Moreover, it can be easily separated from the reaction solution through magnetic decantation using an external magnet, and recycled at least six times without notable reduction in its activity.
Topics & Concepts
SuperparamagnetismCatalysisSulfonic acidAnthranilic acidChemistryAcetic anhydrideGuanidineSolventMagnetic nanoparticlesNuclear chemistryMicrowave irradiationNanoparticleChemical engineeringOrganic chemistryMaterials scienceNanotechnologyMagnetizationQuantum mechanicsMagnetic fieldEngineeringPhysicsQuinazolinone synthesis and applicationsMulticomponent Synthesis of HeterocyclesMicrowave-Assisted Synthesis and Applications