Optimization of magnetic nanoparticles for engineering erythrocytes as theranostic agents
Laura Maria Slavu, A. Antonelli, Emanuele Salvatore Scarpa, Pasant Abdalla, Claire Wilhelm, Niccolò Silvestri, Teresa Pellegrino, Konrad Scheffler, Mauro Magnani, Rosaria Rinaldi, Riccardo Di Corato
Abstract
The synthesis of magnetic nanoparticles (based on iron oxide or Zn/Mn ferrite) has been optimized, through the evaluation of different parameters, for encapsulation into human and murine red blood cells.
Topics & Concepts
BiocompatibilityNanoparticleMononuclear phagocyte systemNanotechnologyDrug deliveryMagnetic nanoparticlesBiocompatible materialIron oxide nanoparticlesChemistryMaterials scienceBiomedical engineeringMedicineOrganic chemistryImmunologyBiologyNanoparticle-Based Drug DeliveryCharacterization and Applications of Magnetic NanoparticlesErythrocyte Function and Pathophysiology