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Age‐specific reference intervals for plasma amino acids and their associations with nutrient intake in the Chinese pediatric population

Yang Wen, Qing Liu, Hongbo Zeng, Lina Lyu, Xiaoling He, Xin Zhang, Wentao Lyu, Weijun Chen, Yingping Xiao

2025iMeta15 citationsDOIOpen Access PDF

Abstract

A total of 2901 healthy Chinese children aged 0-12 years were enrolled in the reference group; 102 confirmed Phenylketonuria cases were included as validation individuals. Establishing the age-specific reference intervals of 42 plasma amino acids in Chinese pediatric populations. Profiling dynamic interactions between multiple nutrient intake and amino acid change patterns.

Topics & Concepts

NutrientPopulationPlasma concentrationInternal medicineAnimal scienceBiologyEndocrinologyDemographyMedicinePhysiologyEnvironmental healthEcologySociologyMetabolism and Genetic DisordersMuscle metabolism and nutritionMetabolomics and Mass Spectrometry Studies