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TRIP13 regulates DNA repair pathway choice through REV7 conformational change

Connor S. Clairmont, Prabha Sarangi, Karthikeyan Ponnienselvan, Lucas D. Galli, Isabelle Csete, Lisa A. Moreau, Guillaume Adelmant, Dipanjan Chowdhury, Jarrod A. Marto, Alan D. D’Andrea

2020Nature Cell Biology161 citationsDOIOpen Access PDF

Topics & Concepts

DNA repairDNA damagePolymeraseDNARegulatorPoly ADP ribose polymeraseCell biologyChemistryBiologyCancer researchMolecular biologyBiochemistryGeneDNA Repair MechanismsPARP inhibition in cancer therapyGenetic factors in colorectal cancer
TRIP13 regulates DNA repair pathway choice through REV7 conformational change | Litcius