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Rethinking the mutation hypotheses of plant organellar DNA

Jie Wang, Yi Zou, Jeffrey P. Mower, Wayne Reeve, Zhiqiang Wu

2024Genomics Communications40 citationsDOIOpen Access PDF

Abstract

A recent analysis of genome copy numbers has demonstrated that reduced availability of homologous templates accelerates nucleotide substitution rates in plant mitochondrial DNA likely due to insufficient repair efficiency, reinforcing the importance of homologous recombination in plant DNA damage repair. This finding drives us to consider and compare the relevant hypotheses of the raising and variable mutation for plant organellar DNA, concluding that no single mechanism has a full explanation.

Topics & Concepts

MutationGeneticsBiologyDNAComputational biologyEvolutionary biologyGeneChromosomal and Genetic VariationsPlant Reproductive BiologyGenomics and Phylogenetic Studies