Micellar catalysis: a green solution to enable undirected and mild C–H activation of (oligo)thiophenes at the challenging β-position
Pascal Hauk, Valérie Mazan, Fabrice Gallou, Joanna Wencel‐Delord
Abstract
The unexpected potential of micellar medium to achieve challenging β-selective direct arylation of (oligo)thiophenes is reported. Thanks to the use of a water/surfactant solution in combination with natural feedstock-derived undecanoic acid as an additive, this high-yielding C-H coupling could be performed regioselectively at room temperature.
Topics & Concepts
CatalysisPosition (finance)ChemistryStereochemistryCombinatorial chemistryOrganic chemistryBusinessFinanceCatalytic C–H Functionalization MethodsSulfur-Based Synthesis TechniquesSynthesis and Catalytic Reactions